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Bridge the gap to space
Access, infrastructure and intelligence beyond Earth.
We back founders building something hard from a unique edge in science — the people inventing the industries that will thrive for decades to come. If that's you, pitch us.
It takes an unreasonable belief to achieve the impossible. That belief — backed by deep science — is exactly what we invest in.
Main Sequence was custom-built for deep tech. We work with inventors turning hard science and difficult engineering into companies the world hasn't seen yet — then we get hands-on to accelerate the path to scale.
We invest in early-stage startups — and inventors who want to start one — with science at their core. Here's what we look for.
You're going after something that matters at planetary scale. See the six challenges we're most excited to solve and consider how you fit.
Your solution depends on cutting-edge science or difficult engineering that you and your team are uniquely able to deliver.
We invest in company foundation through Seed, Series A and Series B — from the very first idea through to mature companies.
Our investments connect with Australian publicly-funded research. It needn't exist yet — be ready to articulate how you could work with a university or CSIRO. Bring the science problems; we'll explore them with you.
We love companies solving one or more of these. Tell us which one is yours.
Access, infrastructure and intelligence beyond Earth.
The technologies that bend the emissions curve.
Compute, models and the hardware underneath them.
Food and agriculture for a hungrier, hotter world.
Care that reaches everyone, not just the few.
Materials, robotics and the future of how we make things.
Deep tech inventors need more than a cheque. We built Main Sequence to give it to you.
From day one you draw on infrastructure, expertise and a reputation it would take decades and billions to build alone.
Scientists across most fields of science.
Of research infrastructure to build on.
Australia's largest patent portfolio.
Universities within close reach.
Build, test and scale up in real facilities.
Trusted validation the world recognises.
Operators who've done it, building with you.
Hiring and team-building support that scales.
Brand and product design on tap.
Tell your story so the world listens.
A working model to compress years into months.
A global reputation that opens doors.
A few of the inventors we've recently backed. Yours could be next.
Tell us about the impossible thing you're building. The more clearly you frame the problem, the science behind your solution, and your research connection, the faster we can move.